Введение
Roman Thaler et al., “Anabolic and Antiresorptive Modulation of Bone Homeostasis by the Epigenetic Modulator Sulforaphane, a Naturally Occurring Isothiocyanate”, Journal of Biological Chemistry 291 (March 2016): 6754–6771. DOI: 10.1074/jbc.M115.678235.
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Глава 1
Raj Chetty et al., “The Association Between Income and Life Expectancy in the United States, 2001–2014”, Journal of the American Medical Association 315, no. 16 (April 26, 2016): 1750–1766. DOI: 10.1001/jama.2016.4226.
Глава 3
Wei-Yi Ong et al., “Protective Effects of Ginseng on Neurological Disorders”, Frontiers in Aging Neuroscience 7, no. 129 (July 2015). DOI: 10.3389/fnagi.2015.00129.
Jared Diamond, “The Worst Mistake in the History of the Human Race (from the May 1987 issue)”, Discover Magazine, May 1, 1999, http://discovermagazine.com/1987/may/02-the-worst-mistake-in-the-history-of-the-human-race.
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Bogdan Draganski et al., “Temporal and Spatial Dynamics of Brain Structure Changes during Extensive Learning”, Journal of Neuroscience 26, no. 23 (June 7, 2006): 6314–6317.
Глава 4
“The Medicare Prescription Drug Benefit Fact Sheet”, Kaiser Family Foundation, September 19, 2014, http://www.kaiseredu.org/Issue-Modules/Prescription-Drug-Costs/Background-Brief.aspx.
Kathrin Endt et al., “The Microbiota Mediates Pathogen Clearance from the Gut Lumen after Non-Typhoidal Salmonella Diarrhea”, PLoS Pathogens 6, no. 9 (September 9, 2010), https://doi.org/10.1371/journal.ppat.1001097.
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Magalie Lenoir et al., “Intense Sweetness Surpasses Cocaine Reward”, PLoS One 2, no. 8 (2007): e698. DOI: 10.1371/journal.pone.0000698.
Kokab Namkin, Mahmood Zardast, and Fatemeh Basirinejad, “Saccharomyces boulardii in Helicobacter pylori Eradication in Children: A Randomized Trial from Iran”, Iranian Journal of Pediatrics 26, no. 1 (February 2016): e3768. DOI: 10.5812/ijp.3768.
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A. Fasano, “Zonulin and Its Regulation of Intestinal Barrier Function: The Biological Door to Inflammation, Autoimmunity, and Cancer”, Physiological Reviews 91, no. 1 (Jan 2011): 151–75. DOI: 10.1152/physrev.00003.2008.
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Els van Nood et al., “Duodenal Infusion of Donor Feces for Recurrent Clostridium difficile”, New England Journal of Medicine 368, no. 5 (January 31, 2013): 407–415.
Глава 5
Ioannis Delimaris, “Adverse Effects Associated with Protein Intake above the Recommended Dietary Allowance for Adults”, ISRN Nutrition 2013, (June 2013), Article ID 126929. DOI: 10.5402/2013/126929.
M. N. Corradetti and K. – L. Guan, “Upstream of the Mammalian Target of Rapamycin: Do All Roads Pass Through mTOR?”, Oncogene 25 (16 October 2006): 6347–6360. DOI: 10.1038/sj.onc.1209885.
Luigi Fontana et al., “Long-Term Effects of Calorie or Protein Restriction on Serum IGF-1 and IGFBP-3 Concentration in Humans”, Aging Cell 7, no. 5 (October 2008): 681–687. DOI: 10.1111/j.14749726.2008.00417.x.
Roberto Zoncu, Alejo Efeyan, and David M. Sabatini, “mTOR: From Growth Signal Integration to Cancer, Diabetes and Ageing”, Nature Reviews Molecular Cell Biology 12, no. 1 (January 2011): 21–35. DOI: 10.1038/nrm3025.
Luigi Fontana et al., “Decreased Consumption of Branched Chain Amino Acids Improves Metabolic Health”, Cell Reports 16, no. 2 (July 12, 2016): 520–530. DOI: 10.1016/j.celrep.2016.05.092.
Chia-Wei Cheng et al., “Prolonged Fasting Reduces IGF-1/PKA to Promote Hematopoietic-Stem-Cell-Based Regeneration and Reverse Immunosuppression”, Cell Stem Cell 13, no. 6 (June 5, 2014): 810–823. https://www.sciencedirect.com/science/article/pii/S 1934590914001519.
Suzanne Wu, “Fasting Triggers Stem Cell Regeneration of Damaged, Old Immune System”, USC News, June 5, 2014, https://news.usc.edu/63669/fasting-triggers-stem-cell-regeneration-of-damaged-old-immune-system/.
Marwan A. Maalouf, Jong M. Rho, and Mark P. Mattson, “The Neuroprotective Properties of Calorie Restriction, the Ketogenic Diet, and Ketone Bodies”, Brain Research Reviews 59, no. 2 (March 2009): 293–315. DOI: 10.1016/j.brainresrev.2008.09.002.
Penny Kris-Etherton et al., “AHA Science Advisory: Lyon Diet Heart Study. Benefits of a Mediterranean-Style, National Cholesterol Education Program/American Heart Association Step I Dietary Pattern on Cardiovascular Disease”, Circulation 103, no. 13 (April 3, 2001): 1823–1825.
Глава 6
Hervé Vaucheret and Yves Chupeau, “Ingested Plant miRNAs Regulate Gene Expression in Animals”, Cell Research 22, no. 1 (January 2012): 3–5.
Jo Robinson, “Breeding the Nutrition Out of Our Food”, New York Times, May 25, 2013, http://www.nytimes.com/2013/05/26/opinion/sunday/breeding-the-nutrition-out-of-our-food.html?smid=pl-share.
Kaitlyn N. Lewis, James Mele, John D. Hayes, and Rochelle Buffenstein, “Nrf2, a Guardian of Healthspan and Gatekeeper of Species Longevity”, Integrative and Comparative Biology 50, no. 5 (November 2010): 829–843. DOI: 10.1093/icb/icq034.
Britta Harbaum et al., “Identification of Flavonoids and Hydroxycinnamic Acids in Pak Choi Varieties (Brassica campestris L. ssp. chinensis var. communis) by HPLC-ESI – MSn and NMR and Their Quantification by HPLC-DAD”, Journal of Agricultural and Food Chemistry 55, no. 20 (October 3, 2007): 8251–8260.
Haitao Luo et al., “Kaempferol Inhibits Angiogenesis and VEGF Expression through Both HIF Dependent and Independent Pathways in Human Ovarian Cancer Cells”, Nutrition and Cancer 61, no. 4 (2009): 554–563.
Morgan E. Levine et al., “Low Protein Intake Is Associated with a Major Reduction in IGF-1, Cancer, and Overall Mortality in the 65 and Younger but Not Older Population”, Cell Metabolism 19, no. 3 (March 2014): 407–417. DOI: 10.1016/j.cmet.2014.02.006.
Thanks to Larry Furtsch of the American Museum of Natural History for this information.
Sally Fallon and Mary G. Enig, Ph.D., “Lacto-Fermentation”, The Weston A. Price Foundation, January 1, 2000, http://www.westonaprice.org/food-features/lacto-fermentation.
Elizabeth P. Ryan et al., “Rice Bran Fermented with Saccharomyces boulardii Generates Novel Metabolite Profiles with Bioactivity”, Journal of Agricultural and Food Chemistry 59, no. 5 (March 9, 2011): 1862–1870. DOI: 10.1021/jf1038103.
Martha Clare Morris, Sc.D., et al., “Consumption of Fish and N-3 Fatty Acids and Risk of Incident Alzheimer Disease”, Archives of Neurology 60, no. 7 (July 2003): 940–946.
J. S. Buell, Ph.D., et al., “25-Hydroxyvitamin D, Dementia, and Cerebrovascular Pathology in Elders Receiving Home Services”, Neurology 74, no. 1 (January 5, 2010): 18–26.
Michael F. Holick, M.D., Ph.D., “Vitamin D Deficiency”, New England Journal of Medicine 357, no. 3 (July 19, 2007): 266–281.
Глава 7
Joyce C. McCann and Bruce N. Ames, “Vitamin K, an Example of Triage Theory: Is Micronutrient Inadequacy Linked to Diseases of Aging?”, The American Journal of Clinical Nutrition 90, no. 4 (1 October 2009): 889–907. DOI: 10.3945/ajcn.2009.27930.
John Neustadt and Steve R. Pieczenik, “Medication-Induced Mitochondrial Damage and Disease”, Molecular Nutrition & Food Research 52, no. 7 (July 2008): 780.
Reiner J. Klement and Ulrike Kämmerer, “Is There a Role for Carbohydrate Restriction in the Treatment and Prevention of Cancer?”, Nutrition & Metabolism 8, no. 75 (October 2011), http://www.nutritionandmetabolism.com/content/pdf/1743–7075–8–75.pdf.
George F. Cahill and Richard L. Veech, “Ketoacids? Good Medicine?”, Transactions of the American Clinical and Climatological Association 114 (2003): 149–163.
W. F. Stewart et al., “Risk of Alzheimer’s Disease and Duration of NSAID Use”, Neurology 48, no. 3 (March 1997): 626–632. PMID: 9065537.
H. Chen et al., “Nonsteroidal Anti-inflammatory Drugs and the Risk of Parkinson’s Disease”, Annals of Neurology 58, no. 6 (December 2005): 963–967. DOI: 10.1002/ana.20682.
Глава 8
Jill Bolte Taylor, Ph.D., My Stroke of Insight: A Brain Scientist’s Personal Journey (New York: Viking Penguin, 2008), 146.
Richard Horton, “Offline: What Is Medicine’s 5 Sigma?”, Lancet 385, no. 9976 (April 11, 2015): 1380. DOI: 10.1016/S 0140–6736(15)60696–1.
Douglas Dean and John Mihalasky, Executive ESP (Englewood Cliffs, NJ: Prentice-Hall, 1974).
Daniel Kahneman, Thinking, Fast and Slow (New York: Farrar, Straus and Giroux, 2011), 11.
Peter Gray, Ph.D., “The Decline of Play and Rise in Children’s Mental Disorders”, Psychology Today, January 26, 2010, http://www.psychologytoday.com/blog/freedom-learn/201001/the-decline-play-and-rise-in-childrens-mental-disorders; “Any Mental Illness (AMI) among Adults”, National Institute of Mental Health, http://www.nimh.nih.gov/statistics/1ANY-DIS_adult.shtml; “Major Depression among Adults”, National Institute of Mental Health, http://www.nimh.nih.gov/health/statistics/prevalence/major-depression-among-adults.shtml; “Any Anxiety Disorder among Adults”, National Institute of Mental Health, http://www.nimh.nih.gov/health/statistics/prevalence/any-anxiety-disorder-among-adults.shtml.
Jean M. Twenge et al., “Birth Cohort Increases in Psychopathology among Young Americans, 1938–2007: A Cross-Temporal Meta-analysis of the MMPI”, Clinical Psychology Review 30, no. 2 (March 2010): 152.
William J. Broad, “Seeker, Doer, Giver, Ponderer”, New York Times, July 7, 2014, D 1.
Глава 9
Carl Jung, “The Concept of the Collective Unconscious”, in The Portable Jung, ed. Joseph Campbell (New York: Viking Penguin, 1971), 60.
Глава 11
Rainer J. Klement and Ulrike Kämmerer, “Is There a Role for Carbohydrate Restriction in the Treatment and Prevention of Cancer?”, Nutrition & Metabolism 8, no. 75 (October 2011), http://www.nutritionandmetabolism.com/content/pdf/1743–7075–8–75.pdf.
Глава 12
Stephen Mitchell, Bhagavad Gita: A New Translation (New York: Three Rivers Press, 2000), 95.
Mitchell, Bhadavad Gita, 21.
Mitchell, Bhadavad Gita, 88.
Глава 13
Marta Alda et al., “Zen Meditation, Length of Telomeres, and the Role of Experiential Avoidance and Compassion”, Mindfulness 7, no. 3 (June 2016): 651–659. DOI: 10.1007/s12671–016–0500–5.
The Essential Rumi, trans. Coleman Barks with John Moyne (San Francisco: HarperSanFrancisco, 1995), 30.
“Nagara Sutta: The City”, Sutta Nipata 12:65, trans. Thanissaro Bhikkhu (1997), http://www.accesstoinsight.org/tipitaka/sn/sn12/sn12.065.than.html.
Chögyam Trungpa, The Truth of Suffering and the Path of Liberation, ed. Judith L. Lief (Boston: Shambhala Publications, 2009), 49.
Dalai Lama, “10 Questions for the Dalai Lama”, Time, June 14, 2010, http://content.time.com/time/magazine/article/0,9171,1993865,00.html.
Глава 14
Edwin A. M. Gale, “The Rise of Childhood Type 1 Diabetes in the 20th Century”, Diabetes 51, no. 12 (December 2002): 3353–3361.
Dean Ornish et al., “Changes in Prostate Gene Expression in Men Undergoing an Intensive Nutrition and Lifestyle Intervention”, Proceedings of the National Academy of Sciences USA 105, no. 24 (June 2008): 8369–8374.
Глава 15
Johns Hopkins University Bloomberg School of Public Health, “US Autism Rate Unchanged in New CDC Report: Researchers Say It’s Too Early to Tell If Rate Has Stabilized”, ScienceDaily, March 31, 2016, www.science-daily.com/releases/2016/03/160331154247.htm.
Ingmar Skoog et al., “Decreasing Prevalence of Dementia in 85-Year-Olds Examined 22 Years Apart: The Influence of Education and Stroke”, Scientific Reports 7, no. 6136 (2017).
F. B. Hu et al., “Frequent Nut Consumption and Risk of Coronary Heart Disease in Women: Prospective Cohort Study”, BMJ 317, no. 7169 (November 14, 1998): 1341–1345.
Jae Kwang Kim and Sang Un Park, “Current Potential Health Benefits of Sulforaphane”, EXCLI Journal 15 (October 13, 2016): 571–577. DOI: 10.17179/excli2016–485.
Parris M. Kidd, Ph. D., “Glutathione: Systemic Protectant Against Oxidative and Free Radical Damage”, Alternative Medicine Review 2, no. 3 (1997): 155–176.
Jeffrey D. Peterson et al., “Glutathione Levels in Antigen-Presenting Cells Modulate Th1 Versus Th2 Response Patterns”, Proceedings of the National Academy of Sciences USA 95, no. 6 (March 17, 1998): 3071–3076.
Jess Gomez, “New Research Finds Routine Periodic Fasting Is Good for Your Health, and Your Heart”, Intermountain Healthcare, April 3, 2011, http://intermountainhealthcare.org/about/careers/working/news/pages/home.aspx? NewsID=71.
Глава 18
Mikhail V. Blagosklonny, “Why Human Lifespan Is Rapidly Increasing: Solving ‘Longevity Riddle’ with ‘Revealed Slow Aging’ Hypothesis”, Aging (Albany NY) 2, no. 4 (April 2010): 177–182. DOI: 10.18632/aging.100139.
J. Gallinetti, E. Harputlugil, and J. R. Mitchell, “Amino Acid Sensing in Dietary-Restriction-Mediated Longevity: Roles of Signal-Transducing Kinases GCN 2 and TOR”, Biochemical Journal 449, no. 1 (January 1, 2013): 1–10. DOI: 10.1042/BJ20121098.
Bodo C. Melnik, “Leucine Signaling in the Pathogenesis of Type 2 Diabetes and Obesity”, World Journal of Diabetes 3, no. 3 (March 15, 2012): 38–53. DOI: 10.4239/wjd.v3.i3.38.
Rainer J. Klement and Ulrike Kämmerer, “Is There a Role for Carbohydrate Restriction in the Treatment and Prevention of Cancer?”, Nutrition & Metabolism 8 (2011): 75. DOI: 10.1186/1743–7075–8–75.
S. Yusuf et al., “Effect of Potentially Modifiable Risk Factors Associated with Myocardial Infarction in 52 Countries (the INTERHEART Study): Case-Control Study”, Lancet 364, no. 9438 (September 11–17, 2004): 937–52.
The Nutrition Source, What Should I Eat? “Vegetables and Fruits”, Harvard T. H. Chan School of Public Health, https://www.hsph.harvard.edu/nutritionsource/what-should-you-eat/vegetables-and-fruits.
P. Knekt et al., “Serum Vitamin D and the Risk of Parkinson Disease”, Archives of Neurology 67, no. 7 (July 2010): 808–811. DOI: 10.1001/archneurol.2010.120.
M. C. Morris et al., “Consumption of Fish and N-3 Fatty Acids and Risk of Incident Alzheimer Disease”, Archives of Neurology 60, no. 7 (July 2003): 940–946.
“Burning More Calories Associated with Greater Gray Matter Volume in Brain, Reduced Alzheimer’s Risk”, UPMC/University of Pittsburgh Schools of the Health Sciences, March 11, 2016, http://www.upmc.com/media/NewsReleases/2016/Pages/gray-matter.aspx.
Penny Baron, “The 10 Most Important Blood Tests”, Life Extension Magazine, May 2006, http://www.lifeextension.com/magazine/2006/5/report_blood/Page-01.
Заключение
Joseph Campbell, The Hero with a Thousand Faces (Novato, CA: New World Library, 2008), 205.
Swami Nikhilananda, trans., The Bhagavad Gita (New York: Ramakrishna-Vivekananda Center, 1944), 77–78.
Jean-Louis Santini, “Are Brains Shrinking to Make Us Smarter?”, Discovery News, February 6, 2011, https://phys.org/news/2011–02-brains-smarter.html.
Campbell, Hero with a Thousand Faces, 142.